Molecular Archives

Posted inin Molecular

How the Salt-Out Method Performs DNA Extraction: Key Scientific Insights

Posted byby Franklin Veaux
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3 min

How Does the Salt-Out Method of DNA Extraction Work, Scientifically? The salt-out method of DNA extraction works by first neutralizing the DNA’s negatively charged phosphate backbone with high concentrations of...

Posted inin Molecular

Top Universities in the East Coast and D.C. Area for Molecular Biology Programs

Posted byby Franklin Veaux
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2 min

Universities in the East Coast and Washington, D.C. Area Good for Molecular Biology The East Coast and Washington, D.C. offer several top-tier universities known for strong Molecular Biology programs. These...

Posted inin Molecular

Optimizing psPAX2 and pMD2.G Plasmid Yield: Key Strategies and Insights

Posted byby Franklin Veaux
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3 min

Understanding psPAX2 and pMD2.G Plasmid Yield The yield of psPAX2 plasmid is generally consistent and high when proper bacterial strains and conditions are used, while pMD2.G yield tends to be...

Posted inin Molecular

Understanding the Link Between Inflammation and Cancer Development

Posted byby Franklin Veaux
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5 min

How Does Inflammation Cause Cancer? Inflammation contributes to cancer primarily through chronic exposure to reactive oxygen and nitrogen species (RONS), which cause DNA damage, and by inducing molecular changes such...

Posted inin Molecular

Some Codon Optimized Genes Show Variability in Performance and Expression Efficiency

Posted byby Franklin Veaux
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7 min

Some Codon Optimized Genes Are Better Than Others Codon-optimized genes differ in their performance due to the complexity of gene expression, which depends on various factors beyond simple codon frequency....

Posted inin Molecular

Availability of ZiFiT Software Copies from the Zinc-Finger Consortium

Posted byby Franklin Veaux
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1 min

Availability and Copies of ZiFiT Software There is no confirmed public information about unauthorized copies of the ZiFiT software from the Zinc Finger Consortium. ZiFiT (Zinc Finger Targeter) is a...

Posted inin Molecular

Molecular Cell Biology Exam Question: Insights on Protein Orientation and Localization

Posted byby Franklin Veaux
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2 min

Molecular Cell Biology Exam Question: Protein Transmembrane Orientation and Localization Proteins with two transmembrane domains typically span a single membrane twice, resulting in an orientation where the C-terminus resides in...

Posted inin Molecular

Top High-Fidelity cDNA Synthesis Kits for Cloning With Bonus qPCR Options

Posted byby Franklin Veaux
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5 min

Recommendations for High-Fidelity cDNA Synthesis Kits for Cloning High-fidelity cDNA synthesis kits suitable for cloning include LunaScript, SuperScript IV, and SuperScript VILO. Among these, SuperScript IV also shows excellent performance...

Posted inin Molecular

CRISPR/Cas and Cancer Treatment: Innovations, Challenges, and the Future of Gene Editing in Oncology

Posted byby Franklin Veaux
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5 min

CRISPR/Cas and Cancer Treatment CRISPR/Cas offers promising avenues for cancer treatment, but challenges in delivery, accuracy, and safety limit its current clinical use. Delivery Efficiency of Cas9 to Cancer Cells...

Posted inin Molecular

Recent Scientific Discoveries: Highlights, Key Breakthroughs, and CRISPR Advances

Posted byby Franklin Veaux
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2 min

Recent Discoveries in Science: Key Highlights and Advances Recent discoveries include major advances such as CRISPR technology improvements, CAR-T therapies, protein structure prediction, and the targeting of difficult proteins like...